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Epidemiological and clinical data from the recent SARS-CoV-2 pandemic indicate that the highest mortality rate is observed in patients suffering from metabolic diseases including obesity and diabetes (62, 63)
Harrison SA, Rinella ME, Abdelmalek MF et al (2018) NGM282 for treatment of non-alcoholic steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial
Blood pressure, lipid panels, and cardiovascular health should be assessed as part of routine care
Hypoxia or genetic alterations leading to stabilization of HIF induce tumor angiogenesis Hyper-proliferation of tumor cells results in increased oxygen consumption, and when the tumor mass surpass the blood supply the tumor becomes hypoxic